But giving money to a disease-specific charity is a very odd, and peculiarly ineffective, way of spending your philanthropic dollar—especially when your donation is a one-off thing. What is the ALS Association going to do with all this money? They haven’t said. The organization’s primary focus is scientific: They fund research into the disease and potential cures. ALS is a tough nut to crack, however: After 30 years of work, we don’t seem to be any closer to finding a cure. And there’s no particular reason to believe that we’re $100 million away from finally getting somewhere. Even if a million Americans donate $100 each to ALS, the net positive effect on the world might well be very small indeed. — ALS Ice Bucket Challenge: Giving money to disease-specific charities is a bad idea.